Tumor cell detection in Lymph Nodes
Development of a workflow for the detection and characterization of disseminated tumor cells in histopathologically negative lymph nodes of patients with head and neck cancer.
Cell Puncher Pro
In a German-Dutch consortium the Cell Puncher Pro demonstrator has been developed and validated to enable the analysis of individual Circulating Tumor Cells (CTC) to guide cancer therapy.
Single cell antibody production and isolation
Arjan Tibbe, Joska Broekmaat, Fikri Abali, Lisa Oomens, Joris Weersink, Michiel Stevens, Lucas Pronk
CTC enumeration: Parsortix and VyCAP
J Broekmaat, L Oomens, M. Stevens, A. Tibbe, VyCAPBV, Enschede, The Netherlands
Stefan Peter, ANGLE Europe Ltd, Guildford, UK
11th ISMRC, May 3-5 2018, Montpellier France
Post-Enrichment Melanoma Cell Isolation using the VyCAP
Aaron Beasley, Lisa Oomens, Michiel Stevens, Arjan Tibbe, Joska Broekmaat, Elin Gray
11th ISMRC, May 3-5 2018, Montpellier France
Self-Seeding Microwells to Isolate and Expand Single Cells
Kiki C Andree, Fikri Abali, Joost F Swennenhuis, Fiona Passanha, Lisa Oomens, Michiel Stevens, Joska Broekmaat, Leon WMM Terstappen
11th ISMRC, May 3-5 2018, Montpellier France
Single CTC isolation for genetic analysis using Parsortix and VyCAP
J Broekmaat, L Oomens, VyCAPBV, Enschede, The Netherlands
S Peter, ANGLE Europe Ltd, Guildford, UK
ACTC 2017, October 4th – 7th, 2017, Rhodes, Greece
Self-sorting microwells to isolate and expand single circulating tumor cells
Joost F. Swennenhuis, Kiki C. Andree, Fikri Abali, Fiona R. Passanha, Arjan G.J. Tibbe, Joska Broekmaat, Michiel Stevens, Cees J.M. van Rijn, Leon W.M.M. Terstappen
AACR annual meeting 2017, April 1-5, Washington, USA
EpCAM+ and EpCAM-circulating tumor cells in metastatic cancer patients: a multicenter study
Sanne de Wit, M. Manicone, E. Rossi, E.K. Trapp,R. Lampignano,M. Ouhlen, M. Crespo, L.L Zeune, K.C. Andree,J.F. Swennenhuis, R. Vidotto, R. Zamarchi, M. Alunni-Fabbroni, M. Tzschaschel, B. Rack, H. Neubauer, T. Fehm,E. Colomba, F. Farace, P. Flohr, J. De Bono, L.W.M.M. Terstappen
AACR annual meeting 2017, April 1-5, Washington, USA
Liquid biopsy in advanced NSCLC: EpCAM+ and EpCAM-circulating tumor cells, tumor derived extracellular vesicles and cell-free circulating tumor DNA
Sanne de Wit, Menno Tamminga, Ellen Heitzer, Joost F Swennenhuis, Ed Schuuring, Leonie L Zeune, Michael R Speicher, T Jeroen N Hiltermann, Leon WMM Terstappen, Harry JM Groen
AACR annual meeting 2017, April 1-5, Washington, USA
Single cell isolation and DNA analysis from circulating tumor cells using self-sorting nanowell plates
Joost F. Swennenhuis, Arjan G.J. Tibbe, Michiel Stevens, Nikolas H. Stoecklein, Rui Neves, Hien D. Tong, Cees J.M. van Rijn and Leon W.M.M Terstappen
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA
Self-Sorting Nanowell Plate for the Isolation and Characterization of Single Circulating Tumor Cells
Joost Swennenhuis, Arjan Tibbe, Michiel Stevens, Hien Duy Tong, Cees van Rijn, Leon WMM Terstappen
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA
Microfluidic device for DNA amplification of single cancer cells isolated from whole blood by self-seeding micro-wells
Yoonsun Yang, Hoon Suk Rho, Michiel Stevens, Arjan G.J. Tibbe, Han Gardeniers, and Leon W.M.M. Terstappen
MicroTAS 2016
Capture, Detection and Analysis of Circulating Tumor Cells
Jacob Baggerman; Ai Nguyen ;Arjan Tibbe; Stefan Sleijfer; Leon Terstappen; Cees van Rijn
Nanocity 2014, Utrecht, Netherlands
Circulating Tumor Cells in metastatic lung cancer enriched by EpCAM expression and physical characteristics
Sanne de Wit, Guus van Dalum, Joost van Dalum, Aufried T.M. Lenferink, Arjan G.J. Tibbe, Cees J.M. van Rijn, T. Jeroen N. Hiltermann, Harry J.M. Groen, Leon W.M.M. Terstappen
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA
EpCAM negative circulating tumor cells in metastatic lung cancer enriched by filtration
Mutter-de Wit, S., van Dalum, G., Lenferink, A. T. M., Tibbe, A. G. J., van Rijn, C., Hilterman, T. J. N., … Terstappen, L. W. M. M.(2014).
Advances in Circulating Tumor Cells (ACTC), Crete, Greece 2014
Detection of EpCAM negative circulating tumor cells in CellSearch waste
van Dalum, G., Lenferink, A. T. M. and Terstappen, L. W. M. M.
Proceedings: AACR 104th Annual Meeting 2013, Washington,USA
FISH for the confirmation of the cancerous origin of cells on a microsieve
Mulder HW , Swennenhuis JF, Mutter-De Wit S, Tibbe AGJ, Terstappen LWMM
Poster Presenation Saxion University, Enschede, The Netherlands 2015
Key factors for filtration of tumor cells from whole blood
van Dalum, G., Coumans, F. A. W., Beck, M., & Terstappen, L. W. M. M.
Proceedings: AACR annual meeting 2012, Chicago, USA
Single cell in a WGA cup: Open-well whole genome amplification device
Yang, Y. S., Rho, H. S., Stevens, M., Tibbe, A. G. J., Gardeniers, J. G. E., & Terstappen, L. W. M. M. (2014).
Nanocity 2014, Utrecht, Netherlands
Microfluidic device for whole genome amplification of single cancer cells isolated from whole blood
Yang, Y. S., Rho, H. S., Stevens, M., Tibbe, A. G. J., Gardeniers, J. G. E. and Terstappen, L. W. M. M. (2015).
Proceedings: MicroTAS 2015, Gyeongju, South Korea
Microfluidic devices for the interrogation of single circulating tumor cells
Yoon Sun Yang, Hoon Suk Rho, Joost Franciscus Swennenhuis, Michiel Stevens, Arjan G.J. Tibbe, Severine le Gac, Johannes G.E. Gardeniers, Leonardus Wendelinus Mathias Marie Terstappen
Proceedings: AACR Annual Meeting 2016, April 16-20, 2016, Philadelphia
Isolation of CTC from Diagnostic LeukApheresis
Kiki C Andree, Anouk Mentink, Martin Scholz, Roland Kirchner, Rui P Neves, Christiane Driemel, Rita Lampignano, Hans Neubauer, Dieter Niederacher, Johannes C Fischer, Nikolas H Stoecklein, Leon WMM Terstappen
Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA